Human TFF2/Trefoil factor 2 ELISA Kit PicoKine® | Boster EK1233 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human TFF2/Trefoil factor 2 ELISA Kit PicoKine®

catalog :

EK1233

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Huang Z, Zhang X, Lu H, Wu L, Wang D, Zhang Q, et al. Serum trefoil factor 3 is a promising non-invasive biomarker for gastric cancer screening: a monocentric cohort study in China. BMC Gastroenterol. 2014;14:74 pubmed publisher

image

image 1 :

Human TFF2 PicoKine ELISA Kit standard curve

product information

SKU :

EK1233

Product Name :

Human TFF2/Trefoil factor 2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human TFF2 ELISA Kit PicoKine® (96 Tests). Quantitate Human TFF2 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

TFF2

Uniprot ID :

Q03403

Immunogen :

Expression system for standard: NS0; Immunogen sequence: E24-Y129

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Trefoil factor 2

Synonyms :

Trefoil factor 2;Spasmolysin;Spasmolytic polypeptide;SP;TFF2;SML1;

Protein Name :

Trefoil factor 2

Molecular Weight :

14284 MW

Protein Function :

Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity).

Subcellular Localization :

Secreted.

Tissue Specificity :

Stomach

Sequence Similarities :

Contains 2 P-type (trefoil) domains.

Background :

Trefoil factor 2, also known as SP or SML1, is a protein that in humans is encoded by the TFF2 gene. This gene belongs to trefoil family, and members of the trefoil family may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene is mapped to 21q22.3. TFF2 gene consists of 4 exons spanning 5.1 kb, with exons 2 and 3 encoding 1 trefoil domain each, and it is the only gene encoding 2 TFF-domains on separate exons. It has been found that the distribution of TFF2 and pS2 suggests involvement in repair-enhancing mechanisms.

Research Category :

Cell Biology

more info or order :

Boster product webpage