Mouse TNFRSF14/HVEM ELISA Kit PicoKine® | Boster EK1227 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse TNFRSF14/HVEM ELISA Kit PicoKine®

catalog :

EK1227

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1227

Product Name :

Mouse TNFRSF14/HVEM ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse TNFRSF14/HVEM ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Tnfrsf14 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 1pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

TNFRSF14

Uniprot ID :

Q80WM9

Immunogen :

Expression system for standard: CHO; Immunogen sequence: Q29-V207

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<1 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

tumor necrosis factor receptor superfamily, member 14

Synonyms :

Protein Tnfrsf14 ;Tumor necrosis factor receptor superfamily member 14 ;Tnfrsf14 ;

Protein Name :

Protein Tnfrsf14

Molecular Weight :

30171 MW

Background :

Tumor necrosis factor receptor superfamily member 14 (TNFRSF14), also known as HVEM, is a protein that in humans is encoded by the TNFRSF14 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. It is mapped to 1p36.32. HVEM plays an important role in HSV pathogenesis because it enhanced the entry of several wildtype HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T cells. HVEM and BTLA which are form a bidirectional signaling pathway can regulate cell survival and inhibitory responses between interacting cells. HVEM as an important orchestrator of mucosal immunity integrates signals from innate lymphocytes to induce optimal epithelial Stat3 activation, which indicated that targeting HVEM with agonists could improve host defense.

Research Category :

Antiviral Signaling, Cancer, Cytokines, Growth Factors, Growth Factors/Hormones, Immune System Diseases, Immunology, Innate Immunity, Signal Transduction, Tnf Superfamily