Human soluble CD5 ELISA Kit PicoKine® | Boster EK1220 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human soluble CD5 ELISA Kit PicoKine®

catalog :

EK1220

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 2

Reference
Ramos Casals M, Font J, Garcia Carrasco M, Calvo J, Places L, Padilla O, et al. High circulating levels of soluble scavenger receptors (sCD5 and sCD6) in patients with primary Sjögren's syndrome. Rheumatology (Oxford). 2001;40:1056-9 pubmed
Calvo J, Places L, Espinosa G, Padilla O, Vila J, Villamor N, et al. Identification of a natural soluble form of human CD5. Tissue Antigens. 1999;54:128-37 pubmed

image

image 1 :

Human soluble CD5 PicoKine ELISA Kit standard curve

product information

SKU :

EK1220

Product Name :

Human soluble CD5 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human soluble CD5 ELISA Kit PicoKine® (96 Tests). Quantitate Human CD5 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

CD5

Uniprot ID :

P06127

Immunogen :

Expression system for standard: NS0; Immunogen sequence: R25-N371

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

T-cell surface glycoprotein CD5

Synonyms :

T-cell surface glycoprotein CD5;Lymphocyte antigen T1/Leu-1;CD5;CD5;LEU1;

Protein Name :

T-cell surface glycoprotein CD5

Molecular Weight :

54578 MW

Protein Function :

May act as a receptor in regulating T-cell proliferation.

Subcellular Localization :

Cell membrane; Single-pass type I membrane protein.

Background :

CD5, also known as T1 or LEU1, is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. It is mapped to 11q12.2. Although CD5 can be found on both T cells and B cells, T cells express higher levels of CD5 than B cells. CD5 was used as a T-cell marker until monoclonal antibodies against CD3 were developed. CD5 is upregulated on T cells upon strong activation. In the thymus, there is a correlation with CD5 expression and strength of the interaction of the T cell towards self-peptides. Nevertheless, CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins.

Research Category :

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells, T Cells, T Lymphocytic Lineage

more info or order :

Boster product webpage