Mouse HGF/Hepatocyte growth factor ELISA Kit PicoKine®

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse HGF/Hepatocyte growth factor ELISA Kit PicoKine®

catalog :

EK1217

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1217

Product Name :

Mouse HGF/Hepatocyte growth factor ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse HGF/Hepatocyte growth factor ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Hgf in cell culture supernatants, serum and plasma (EDTA, citrate). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

Hgf

Uniprot ID :

Q08048

Immunogen :

Expression system for standard: NS0; Immunogen sequence: Q33-R495 (α) & V496-L728 (β)

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (EDTA, citrate)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Hepatocyte growth factor

Synonyms :

Hepatocyte growth factor;Hepatopoietin-A;Scatter factor;SF;Hepatocyte growth factor alpha chain;Hepatocyte growth factor beta chain;Hgf;

Protein Name :

Hepatocyte growth factor

Molecular Weight :

82945 MW

Protein Function :

Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

Sequence Similarities :

Belongs to the peptidase S1 family. Plasminogen subfamily.

Background :

Hepatocyte growth factor (HGF) is the most potent mitogen for mature parenchymal hepatocytes in primary culture, and seems to be a hepatotrophic factor that acts as a trigger for liver regeneration after partial hepatectomy and liver injury. HGF has a relative molecular mass (Mr) of 82,000 and is a heterodimer composed of a large alpha-subunit of Mr 69,000 and a small beta-subunit of Mr 34,000. The protein consists of 728 amino acid residues, including a possible signal peptide at the N-terminus. HGF may serve as a paracrine mediator to control placental development and growth. This growth factor may play an important role as a paracrine mediator of the proliferation of melanocytes and endothelial cells, as well as cells of epithelial origin. The gene encoding the human HGF is assigned to human chromosome 7.

Research Category :

Signal Transduction