Human beta IG-H3/TGFBI ELISA Kit PicoKine® | Boster EK1202 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human beta IG-H3/TGFBI ELISA Kit PicoKine®

catalog :

EK1202

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1202

Product Name :

Human beta IG-H3/TGFBI ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human beta IG-H3/TGFBI ELISA Kit PicoKine® (96 Tests). Quantitate Human TGFBI in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

TGFBI

Uniprot ID :

Q15582

Immunogen :

Expression system for standard: NS0; Immunogen sequence: G24-H683

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Transforming growth factor-beta-induced protein ig-h3

Synonyms :

Transforming growth factor-beta-induced protein ig-h3;Beta ig-h3;Kerato-epithelin;RGD-containing collagen-associated protein;RGD-CAP;TGFBI;BIGH3;

Protein Name :

Transforming growth factor-beta-induced protein ig-h3

Molecular Weight :

74681 MW

Protein Function :

Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation.

Subcellular Localization :

Secreted, extracellular space, extracellular matrix. May be associated both with microfibrils and with the cell surface.

Tissue Specificity :

Highly expressed in the corneal epithelium.

Sequence Similarities :

Contains 1 EMI domain.

Background :

Transforming growth factor, beta-induced, 68kDa, also known as TGFBI (initially called BIGH3, BIG-H3), is a protein which in humans is encoded by the TGFBI gene. It is mapped to 5q31.1. This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion.

Research Category :

Collagen, Cytoskeleton / Ecm, Developmental Biology, Ecm Proteins, Extracellular Matrix, Growth Factors/Hormones, Neuroscience, Organogenesis, Sensory System, Signal Transduction, Structures, Visual System