Mouse beta IG-H3/TGFBI ELISA Kit PicoKine® | Boster EK1191 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse beta IG-H3/TGFBI ELISA Kit PicoKine®

catalog :

EK1191

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1191

Product Name :

Mouse beta IG-H3/TGFBI ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse beta IG-H3/TGFBI ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Tgfbi in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 5pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

Tgfbi

Uniprot ID :

P82198

Immunogen :

Expression system for standard: NS0; Immunogen sequence: G24-H683

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<5 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Transforming growth factor-beta-induced protein ig-h3

Synonyms :

Transforming growth factor-beta-induced protein ig-h3;Beta ig-h3;Tgfbi;

Protein Name :

Transforming growth factor-beta-induced protein ig-h3

Molecular Weight :

74597 MW

Protein Function :

Plays a role in cell adhesion (PubMed:8024701). May play a role in cell-collagen interactions (By similarity).

Subcellular Localization :

Secreted . Secreted, extracellular space, extracellular matrix . May be associated both with microfibrils and with the cell surface.

Tissue Specificity :

Expressed in heart, kidney, liver, skeletal muscle, testis, thyroid and uterus (PubMed:8024701).

Background :

Transforming growth factor, beta-induced, 68kDa, also known as TGFBI (initially called BIGH3, BIG-H3), is a protein which in humans is encoded by the TGFBI gene. It is mapped to 5q31.1. This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion.

Research Category :

Cytoskeleton / Ecm, Developmental Biology, Ecm Proteins, Extracellular Matrix, Growth Factors/Hormones, Neuroscience, Organogenesis, Sensory System, Signal Transduction, Structures, Visual System