Mouse ACE2 ELISA Kit PicoKine® | Boster EK1188 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse ACE2 ELISA Kit PicoKine®

catalog :

EK1188

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1188

Product Name :

Mouse ACE2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse ACE2 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ace2 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

ACE2

Uniprot ID :

Q8R0I0

Immunogen :

Expression system for standard: CHO; Immunogen sequence: Q18-T740

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Angiotensin-converting enzyme 2

Synonyms :

Angiotensin-converting enzyme 2;3.4.17.23;ACE-related carboxypeptidase;Processed angiotensin-converting enzyme 2;Ace2;

Protein Name :

Angiotensin-converting enzyme 2

Molecular Weight :

92368 MW

Protein Function :

Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. May have a protective role in acute lung injury.

Subcellular Localization :

Processed angiotensin-converting enzyme 2: Secreted .

Tissue Specificity :

Expressed in heart, kidney and forebrain (at protein level). Ubiquitously expressed, with highest levels in ileum, kidney and lung. In lung, expressed on vascular endothelial and airway epithelial cells.

Background :

AngiotensinI-converting enzyme 2 (ACE 2) is a protein belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. By sequence similarity to a sequence in GenBank, this gene is mapped to Xp22.2. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

Research Category :

Cell Biology, Cardiovascular, Proteolysis / Ubiquitin, Contractility, Vasculature, Metalloprotease, Proteolytic Enzymes