Mouse IGFBP5 ELISA Kit PicoKine® | Boster EK1183 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse IGFBP5 ELISA Kit PicoKine®

catalog :

EK1183

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1183

Product Name :

Mouse IGFBP5 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse IGFBP5 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Igfbp5 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

IGFBP5

Uniprot ID :

Q07079

Immunogen :

Expression system for standard: NS0; Immunogen sequence: L20-E271

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Insulin-like growth factor-binding protein 5

Synonyms :

Insulin-like growth factor-binding protein 5;IBP-5;IGF-binding protein 5;IGFBP-5;Igfbp5;Igfbp-5;

Protein Name :

Insulin-like growth factor-binding protein 5

Molecular Weight :

30372 MW

Protein Function :

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Subcellular Localization :

Secreted.

Tissue Specificity :

Most abundant in kidney, uterus and gastrocnemius muscle.

Sequence Similarities :

Contains 1 IGFBP N-terminal domain.

Background :

Insulin-like growth factor-binding protein 5 is a protein that in humans is encoded by the IGFBP5 gene. The IGFBP5 gene was mapped to chromosome 2q33-q34. The expression of IGFBP5 by stable transfection and adenovirus-mediated infection was inhibitory to growth in 2 human breast cancer cell lines. Stable expression of IGFBP5 in the breast cancer cell lines also inhibited the formation and growth of tumors following injection in athymic mice. IGFBP5 is believed a growth inhibitor and proapoptotic agent in breast cancer cells.

Research Category :

Growth Factors/Hormones, Lipid Signaling, Signal Transduction, Signaling Pathway