Mouse Sclerostin/SOST ELISA Kit PicoKine® | Boster EK1179 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse Sclerostin/SOST ELISA Kit PicoKine®

catalog :

EK1179

quantity :

96 wells/kit, with removable strips.

price :

399 USD

more info or order :

Boster product webpage

citations: 1

Reference
Jastrzebski S, Kalinowski J, Stolina M, Mirza F, Torreggiani E, Kalajzic I, et al. Changes in bone sclerostin levels in mice after ovariectomy vary independently of changes in serum sclerostin levels. J Bone Miner Res. 2013;28:618-26 pubmed publisher

image

image 1 :

Mouse Sclerostin/SOST PicoKine ELISA Kit standard curve

product information

SKU :

EK1179

Product Name :

Mouse Sclerostin/SOST ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

399 USD

Description :

Mouse Sclerostin/SOST ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Sost in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

SOST

Uniprot ID :

Q99P68

Immunogen :

Expression system for standard: NS0; Immunogen sequence: Q24-Y211

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Sclerostin

Synonyms :

Sclerostin;Sost;

Protein Name :

Sclerostin

Molecular Weight :

23443 MW

Protein Function :

Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Subcellular Localization :

Secreted, extracellular space, extracellular matrix .

Sequence Similarities :

Belongs to the sclerostin family.

Background :

Sclerostin is a protein that in humans is encoded by the SOST gene. Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation. The SOST gene maps to chromosome 17q12-q21

Research Category :

Cytoskeleton / Ecm, Developmental Biology, Extracellular Matrix, Growth Factors/Hormones, Metabolism, Organogenesis, Secreted, Signal Transduction, Signaling Pathways, Skeletal Development, Stem Cells, Structures

more info or order :

Boster product webpage