Rat TNFSF12/Tweak ELISA Kit PicoKine® | Boster EK1177 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat TNFSF12/Tweak ELISA Kit PicoKine®

catalog :

EK1177

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1177

Product Name :

Rat TNFSF12/Tweak ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Rat TNFSF12/Tweak ELISA Kit PicoKine® (96 Tests). Quantitate Rat Tnfsf12 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

TNFSF12

Uniprot ID :

Q6AYC1

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: S94-H249

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

tumor necrosis factor (ligand) superfamily, member 12

Synonyms :

Protein Prmt2 ;Tumor necrosis factor ligand superfamily member 12 ;Tnfsf12 ;Prmt2 ;

Protein Name :

Tumor necrosis factor ligand superfamily member 12

Molecular Weight :

27381 MW

Background :

Tumor necrosis factor ligand superfamily member 12 also known as TNF-related weak inducer of apoptosis (TWEAK) is a protein that in humans is encoded by the TNFSF12 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator ofangiogenesis. The TNFSF12 gene lies 878 bp upstream of the putative transcriptional start site of the TNFSF13 gene on chromosome 17p13.1.

Research Category :

Apoptosis, Cancer, Cell Biology, Cell Death, Growth Factors, Invasion/Microenvironment