Human SP-D / Surfactant protein D ELISA Kit PicoKine®

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human SP-D / Surfactant protein D ELISA Kit PicoKine®

catalog :

EK1171

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Nishikiori H, Chiba H, Ariki S, Kuronuma K, Otsuka M, Shiratori M, et al. Distinct compartmentalization of SP-A and SP-D in the vasculature and lungs of patients with idiopathic pulmonary fibrosis. BMC Pulm Med. 2014;14:196 pubmed publisher

image

image 1 :

Human SP-D PicoKine ELISA Kit standard curve

product information

SKU :

EK1171

Product Name :

Human SP-D / Surfactant protein D ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human SP-D / Surfactant protein D ELISA Kit PicoKine® (96 Tests). Quantitate Human SFTPD in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 20pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

SFTPD

Uniprot ID :

P35247

Immunogen :

Expression system for standard: NS0; Immunogen sequence: A21-F375

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

625 pg/ml - 40,000 pg/ml

Sensitivity :

<20 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Pulmonary surfactant-associated protein D

Synonyms :

Pulmonary surfactant-associated protein D;PSP-D;SP-D;Collectin-7;Lung surfactant protein D;SFTPD;COLEC7, PSPD, SFTP4;

Protein Name :

Pulmonary surfactant-associated protein D

Molecular Weight :

37728 MW

Protein Function :

Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

Subcellular Localization :

Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.

Tissue Specificity :

Expressed in lung, brain, pancreas and adipose tissue (mainly mature adipocytes).

Sequence Similarities :

Belongs to the SFTPD family.

Background :

Surfactant, pulmonary-associated protein D, also known as SFTPD or SP-D, is a protein which in humans is encoded by the SFTPD gene. By fluorescence in situ hybridization, the SP-D gene was localized in 10q22.2-q23.1. On the basis of homology with other collectins, potential functions for SP-D include roles in innate immunity and surfactant metabolism, SP-D is produced in the bronchiolar and terminal epithelium of human fetal lung from about 21 weeks of gestation. What’s more, SP-A and SP-D act as dual-function surveillance molecules that reverse orientation and function and become initiators of host-defense reactions.

Research Category :

Calcium Binding Proteins, Calcium Signaling, Cancer, Cancer Metabolism, Cell Biology, Defensin, Human Protein, Immunology, Innate Immunity, Macrophage / Inflamm., Metabolism, Microbiology, Oxidative Stress, Pathways And Processes, Protein, Redox Metabolism, Signal Transduction, Signaling Pathway

more info or order :

Boster product webpage