Human KLK13/Kallikrein-13 ELISA Kit PicoKine® | Boster EK1168 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human KLK13/Kallikrein-13 ELISA Kit PicoKine®

catalog :

EK1168

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1168

Product Name :

Human KLK13/Kallikrein-13 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human KLK13/Klk L4 ELISA Kit PicoKine® (96 Tests). Quantitate Human KLK13 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

KLK13

Uniprot ID :

Q9UKR3

Immunogen :

Expression system for standard: NS0; Immunogen sequence: G17-Q277

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Kallikrein-13

Synonyms :

Kallikrein-13;3.4.21.-;Kallikrein-like protein 4;KLK-L4;KLK13;KLKL4;

Protein Name :

Kallikrein-13

Molecular Weight :

30570 MW

Subcellular Localization :

Secreted .

Tissue Specificity :

Expressed in prostate, breast, testis and salivary gland.

Background :

Kallikrein-13 is a protein that in humans is encoded by the KLK13 gene. It belongs to the kallikrein subgroup of serine proteases, which have diverse physiologic functions in many tissues. By genomic sequence analysis, KLK13 gene is mapped in a 300-kb region on chromosome 19q13.3-q13.4. It has been shown that recombinant hK13 produced in yeast can cleave synthetic peptides after the arginine residue and some extracellular matrix components. However, its exact physiological substrates and functions remain obscure. Despite the lack of knowledge on the physiological function of hK13, several studies have demonstrated that hK13 is implicated with cancer of the breast and ovary and it can serve as a favorable prognostic biomarker for these malignancies.

Research Category :

Extracellular Matrix, Invasion/Microenvironment, Proteolysis / Ubiquitin, Proteolytic Enzymes, Signal Transduction