Human KLK12/Klk L5 ELISA Kit PicoKine® | Boster EK1167 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human KLK12/Klk L5 ELISA Kit PicoKine®

catalog :

EK1167

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1167

Product Name :

Human KLK12/Klk L5 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human KLK12/Klk L5 ELISA Kit PicoKine® (96 Tests). Quantitate Human KLK12 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

KLK12

Uniprot ID :

Q9UKR0

Immunogen :

Expression system for standard: NS0; Immunogen sequence: A18-N248

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Kallikrein-12

Synonyms :

Kallikrein-12;3.4.21.-;Kallikrein-like protein 5;KLK-L5;KLK12;KLKL5;UNQ669/PRO1303;

Protein Name :

Kallikrein-12

Molecular Weight :

26734 MW

Subcellular Localization :

Secreted.

Background :

Kallikrein-12 is a protein that in humans is encoded by the KLK12 gene. It belongs to the kallikrein subgroup of serine proteases, which have diverse physiologic functions in many tissues. KLK12 is expressed primarily in salivary gland, stomach, uterus, trachea, prostate, thymus, lung, colon, brain, breast, and thyroid gland and at lower levels in testis, pancreas, small intestine, and spinal cord. The expression of KLK12 is downregulated at the mRNA level in breast cancer tissues and is upregulated by steroid hormones in breast and prostate cancer cell lines.

Research Category :

Cancer, Cell Biology, Cytoskeleton / Ecm, Ecm Enzymes, Extracellular Matrix, Invasion/Microenvironment, Proteolysis / Ubiquitin, Proteolytic Enzymes, Signal Transduction