Mouse GDF-15 ELISA Kit PicoKine® | Boster EK1134 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse GDF-15 ELISA Kit PicoKine®

catalog :

EK1134

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1134

Product Name :

Mouse GDF-15 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse GDF-15 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Gdf15 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

GDF15

Uniprot ID :

Q9Z0J7

Immunogen :

Expression system for standard: NS0; Immunogen sequence: S189-A303

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from sheep, polyclonal antibody from sheep

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Growth/differentiation factor 15

Synonyms :

Growth/differentiation factor 15;GDF-15;Gdf15;Sbf;

Protein Name :

Growth/differentiation factor 15

Molecular Weight :

33225 MW

Subcellular Localization :

Secreted .

Tissue Specificity :

Highly expressed in liver.

Background :

GDF-15 (Growth differentiation factor 15),also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB, is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. Using FISH, the MIC1 gene is mapped to 19p13.2-p13.1. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF15 showed increased expression and secretion during erythroblast maturation. GDF15 functions as an antiinflammatory cytokine by directly interfering with chemokine signaling and integrin activation.

Research Category :

Cardiovascular, Cell Biology, Cell Cycle, Cell Division, Cytokinesis, Cytoskeleton / Ecm, Extracellular Matrix, Growth Factors/Hormones, Hypertrophy, Signal Transduction, Structures