Mouse CCL6/C10 ELISA Kit PicoKine® | Boster EK1125 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse CCL6/C10 ELISA Kit PicoKine®

catalog :

EK1125

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1125

Product Name :

Mouse CCL6/C10 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse CCL6/C10 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ccl6 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

Ccl6

Uniprot ID :

P27784

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: G22-A116

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

C-C motif chemokine 6

Synonyms :

C-C motif chemokine 6;Protein C10;Small-inducible cytokine A6;CCL6 (22-95);CCL6 (23-95);Ccl6;C10, Scya6;

Protein Name :

C-C motif chemokine 6

Molecular Weight :

12984 MW

Protein Function :

CCL6 (22-95) and CCL6 (23-95) are potent chemoattractants.

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed in myelopoietic bone marrow cultures stimulated by GM-CSF.

Background :

Chemokine (C-C motif) ligand 6 (CCL6) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents.In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, and can be greatly induced under conditions suitable for myeloid cell differentiation. It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF. Some low levels of gene expression also occur in certain cell lines of myeloid origin (e.g. the immature myeloid cell lines DA3 and 32D cl3, and the macrophage cell line P388D) that can also be greatly induced in culture with GM-CSF. However, in activated T cell lines, expression of CCL6 is greatly reduced. CCL6 can also be induced in the mouse lung by the cytokine interleukin 13. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.

Research Category :

Chemokines, Immunology, Innate Immunity