Human TNFRSF13C/BAFFR ELISA Kit PicoKine® | Boster EK1121 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human TNFRSF13C/BAFFR ELISA Kit PicoKine®

catalog :

EK1121

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1121

Product Name :

Human TNFRSF13C/BAFFR ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human TNFRSF13C/BAFFR ELISA Kit PicoKine® (96 Tests). Quantitate Human TNFRSF13C in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

TNFRSF13C

Uniprot ID :

Q96RJ3

Immunogen :

Expression system for standard: NS0; Immunogen sequence: S7-A71

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

78 pg/ml - 5,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Tumor necrosis factor receptor superfamily member 13C

Synonyms :

Tumor necrosis factor receptor superfamily member 13C;B-cell-activating factor receptor;BAFF receptor;BAFF-R;BLyS receptor 3;CD268;TNFRSF13C;BAFFR, BR3;

Protein Name :

Tumor necrosis factor receptor superfamily member 13C

Molecular Weight :

18864 MW

Protein Function :

B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.

Subcellular Localization :

Membrane ; Single-pass type III membrane protein .

Tissue Specificity :

Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes.

Background :

Tumor necrosis factor receptor superfamily member 13C also known as B-cell-activating factor receptor or BAFF receptor is a protein that in humans is encoded by the TNFRSF13C gene. By homology to a BAC clone, the BAFFR gene was mapped to chromosome 22q13.1-q13.31. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular phenylalanine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

Research Category :

Growth Factors/Hormones, Signal Transduction