Human CCL15/Mip 1 Delta ELISA Kit PicoKine® | Boster EK1120 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human CCL15/Mip 1 Delta ELISA Kit PicoKine®

catalog :

EK1120

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Arakelyan A, Kriegova E, Kubistova Z, Mrazek F, Kverka M, du Bois R, et al. Protein levels of CC chemokine ligand (CCL)15, CCL16 and macrophage stimulating protein in patients with sarcoidosis. Clin Exp Immunol. 2009;155:457-65 pubmed publisher

image

image 1 :

Human CCL15 PicoKine ELISA Kit standard curve

product information

SKU :

EK1120

Product Name :

Human CCL15/Mip 1 Delta ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human CCL15/Mip 1 Delta ELISA Kit PicoKine® (96 Tests). Quantitate Human CCL15 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

CCL15

Uniprot ID :

Q16663

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: Q22-I113

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

C-C motif chemokine 15

Synonyms :

C-C motif chemokine 15;Chemokine CC-2;HCC-2;Leukotactin-1;LKN-1;MIP-1 delta;Macrophage inflammatory protein 5;MIP-5;Mrp-2b;NCC-3;Small-inducible cytokine A15;CCL15 (22-92);CCL15 (25-92);CCL15 (29-92);CCL15;MIP5, NCC3, SCYA15;

Protein Name :

C-C motif chemokine 15

Molecular Weight :

12248 MW

Protein Function :

Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15 (22-92), CCL15 (25-92) and CCL15 (29-92) are more potent chemoattractants than the small-inducible cytokine A15.

Subcellular Localization :

Secreted.

Tissue Specificity :

Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15 (22-92), CCL15 (25-92) and CCL15 (29-92) are found in high levels in synovial fluids from rheumatoid patients.

Sequence Similarities :

Belongs to the intercrine beta (chemokine CC) family.

Background :

Chemokine (C-C motif) ligand 15 (CCL15) is a small cytokine belonging to the CC chemokine family that is also known as leukotactin-1, MIP5 and HCC-2. CCL15 is expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3. The human CCL15 gene spans four exons and is located in a head-to-tail orientation on chromosome 17 with the gene of another CC chemokine known as CCL14.

Research Category :

Angiogenesis, Cardiovascular, Chemokines, Immunology, Innate Immunity, Macrophage / Inflamm.

more info or order :

Boster product webpage