Bovine TGF-Beta 3 ELISA Kit PicoKine® | Boster EK1103-BV product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Bovine TGF-Beta 3 ELISA Kit PicoKine®

catalog :

EK1103-BV

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Hering S, Isken F, Janott J, Jost C, Pommer A, Muhr G, et al. Analysis of TGFbeta3 gene expression and protein levels in human bone and serum. Exp Clin Endocrinol Diabetes. 2001;109:107-15 pubmed

product information

SKU :

EK1103-BV

Product Name :

Bovine TGF-Beta 3 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Bovine TGF-Beta 3 ELISA Kit PicoKine® (96 Tests). Quantitate Bovine TGFB3 in cell culture supernatants, serum, plasma (EDTA) and urine. Sensitivity: 10pg/ml.

Reactivity :

Bovine

Application :

ELISA

Gene Name :

TGFB3

Uniprot ID :

P10600

Immunogen :

Expression system for standard: NS0; Immunogen sequence: A301-S412

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (EDTA) and urine

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Transforming growth factor beta-3

Synonyms :

Transforming growth factor beta-3;TGF-beta-3;Latency-associated peptide;LAP;TGFB3;

Protein Name :

Transforming growth factor beta-3

Molecular Weight :

47328 MW

Protein Function :

Involved in embryogenesis and cell differentiation.

Subcellular Localization :

Secreted.

Sequence Similarities :

Belongs to the TGF-beta family.

Background :

Transforming growth factor beta 3 (TGF-beta 3) is a type of protein, known as a cytokine, which is involved in cell differentiation, embryogenesis and development. It belongs to a large family of cytokines called the Transforming growth factor beta superfamily. TGF-beta 3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-beta 3, mammals develop a deformity known as acleft palate. This is caused by failure of epithelial cells in both sides of the developing palate to fuse. TGF-beta 3 also plays an essential role in controlling the development of lungs in mammals, by also regulating cell adhesion and ECM formation in this tissue, and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. TGF-beta 3 activated Lef1 in the absence of beta-catenin (CTNNB1) via nuclear phospho-Smad2 and Smad4.

Research Category :

Angiogenesis, Cancer, Growth Factors, Growth Factors/Hormones, Invasion/Microenvironment, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, Tgf Beta

more info or order :

Boster product webpage