Human IGFBP7/Igfbp Rp1 ELISA Kit PicoKine® | Boster EK0991 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human IGFBP7/Igfbp Rp1 ELISA Kit PicoKine®

catalog :

EK0991

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Gu H, Gu T, Hilding A, Zhu Y, Kärvestedt L, Ostenson C, et al. Evaluation of IGFBP-7 DNA methylation changes and serum protein variation in Swedish subjects with and without type 2 diabetes. Clin Epigenetics. 2013;5:20 pubmed publisher

image

image 1 :

Human IGFBP7 PicoKine ELISA Kit standard curve

product information

SKU :

EK0991

Product Name :

Human IGFBP7/Igfbp Rp1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human IGFBP7/Igfbp Rp1 ELISA Kit PicoKine® (96 Tests). Quantitate Human IGFBP7 in cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 20pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

IGFBP7

Uniprot ID :

Q16270

Immunogen :

Expression system for standard: NS0; Immunogen sequence: D30-L282

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

625 pg/ml - 40,000 pg/ml

Sensitivity :

<20 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA) and urine

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Insulin-like growth factor-binding protein 7

Synonyms :

Insulin-like growth factor-binding protein 7;IBP-7;IGF-binding protein 7;IGFBP-7;IGFBP-rP1;MAC25 protein;PGI2-stimulating factor;Prostacyclin-stimulating factor;Tumor-derived adhesion factor;TAF;IGFBP7;MAC25, PSF;

Protein Name :

Insulin-like growth factor-binding protein 7

Molecular Weight :

29130 MW

Protein Function :

Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.

Subcellular Localization :

Secreted.

Sequence Similarities :

Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Background :

Insulin-like growth factor-binding protein 7 is a protein that in humans is encoded by the IGFBP7 gene. The gene was mapped to chromosome 4q12. The major function of the protein is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 binds to IGF with high affinity. It also stimulates cell adhesion. The protein is implicated in some cancers.

Research Category :

Cancer, Growth Factors/Hormones, Oncoproteins/Suppressors, Signal Transduction, Tumor Suppressors

more info or order :

Boster product webpage