Human IL-17RC ELISA Kit PicoKine® | Boster EK0984 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human IL-17RC ELISA Kit PicoKine®

catalog :

EK0984

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Wu W, Jin M, Wang Y, Liu B, Shen D, Chen P, et al. Overexpression of IL-17RC associated with ocular sarcoidosis. J Transl Med. 2014;12:152 pubmed publisher

image

image 1 :

Human IL-17RC PicoKine ELISA Kit standard curve

product information

SKU :

EK0984

Product Name :

Human IL-17RC ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human IL-17RC ELISA Kit PicoKine® (96 Tests). Quantitate Human IL17RC in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 15pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

IL17RC

Uniprot ID :

Q8NAC3

Immunogen :

Expression system for standard: NS0; Immunogen sequence: L21-A454

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

250 pg/ml - 16000 pg/ml

Sensitivity :

<15 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Interleukin-17 receptor C

Synonyms :

Interleukin-17 receptor C;IL-17 receptor C;IL-17RC;Interleukin-17 receptor homolog;IL17Rhom;Interleukin-17 receptor-like protein;IL-17RL;ZcytoR14;IL17RC;UNQ6118/PRO20040/PRO38901;

Protein Name :

Interleukin-17 receptor C

Molecular Weight :

86240 MW

Subcellular Localization :

Cell membrane; Single-pass type I membrane protein. Soluble isoforms may be produced.

Tissue Specificity :

Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate. Low expression in thymus and leukocytes. Expressed (at protein level) in prostate and prostate cancer, skeletal muscle, kidney and placenta.

Background :

Interleukin-17 receptor C is a protein that in humans is encoded by the IL17RC gene. By genomic sequence analysis, IL17RC gene was mapped to chromosome 3p25.3-p24.1. This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date. The biologic activity of IL-17 is dependent on a complex composed of IL-17RA and IL-17RC, suggesting a new paradigm for understanding the interactions between the expanded family of IL-17 ligands and their receptors.

Research Category :

Cytokines, Immunology, Innate Immunity, Interleukins

more info or order :

Boster product webpage