Human Betacellulin/BTC ELISA Kit PicoKine® | Boster EK0980 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Betacellulin/BTC ELISA Kit PicoKine®

catalog :

EK0980

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0980

Product Name :

Human Betacellulin/BTC ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human Betacellulin/BTC ELISA Kit PicoKine® (96 Tests). Quantitate Human BTC in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

BTC

Uniprot ID :

P35070

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: D32-Y111

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Probetacellulin

Synonyms :

Probetacellulin;Betacellulin;BTC;BTC;

Protein Name :

Probetacellulin

Molecular Weight :

19746 MW

Protein Function :

Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.

Subcellular Localization :

Betacellulin: Secreted, extracellular space.

Tissue Specificity :

Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.

Background :

Betacellulin, also known as BTC is a protein that in humans is encoded by the BTC gene. This gene is mapped to 4q13.3. The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. It is the growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. This protein is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.

Research Category :

Cancer, Growth Factors, Growth Factors/Hormones, Signal Transduction