Human IL-31/Interleukin-31 ELISA Kit PicoKine® | Boster EK0979 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human IL-31/Interleukin-31 ELISA Kit PicoKine®

catalog :

EK0979

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Ezzat M, Hasan Z, Shaheen K. Serum measurement of interleukin-31 (IL-31) in paediatric atopic dermatitis: elevated levels correlate with severity scoring. J Eur Acad Dermatol Venereol. 2011;25:334-9 pubmed publisher

image

image 1 :

Human IL-31 PicoKine ELISA Kit standard curve

product information

SKU :

EK0979

Product Name :

Human IL-31/Interleukin-31 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human IL-31 ELISA Kit PicoKine® (96 Tests). Quantitate Human IL31 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

IL31

Uniprot ID :

Q6EBC2

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: S24-T164

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Interleukin-31

Synonyms :

Interleukin-31;IL-31;IL31;

Protein Name :

Interleukin-31

Molecular Weight :

18205 MW

Protein Function :

Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.

Subcellular Localization :

Secreted .

Tissue Specificity :

Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.

Background :

Interleukin-31, also known as IL-31 is a protein that in humans is encoded by the IL31 gene. This gene is mapped to 12q24.31. IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA and OSMR that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma. IL31 may function in skin immunity.

Research Category :

Cytokines, Immunology, Innate Immunity, Interleukins

more info or order :

Boster product webpage