Rat CRP/C Reactive Protein ELISA Kit PicoKine® | Boster EK0978 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat CRP/C Reactive Protein ELISA Kit PicoKine®

catalog :

EK0978

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0978

Product Name :

Rat CRP/C Reactive Protein ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Rat CRP/C Reactive Protein ELISA Kit PicoKine® (96 Tests). Quantitate Rat Crp in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

CRP

Uniprot ID :

P48199

Immunogen :

Expression system for standard: NS0; Immunogen sequence: H20-S230

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

C-reactive protein

Synonyms :

C-reactive protein;Crp;Ptx1;

Protein Name :

C-reactive protein

Molecular Weight :

25468 MW

Protein Function :

Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity).

Subcellular Localization :

Secreted.

Tissue Specificity :

Found in plasma.

Sequence Similarities :

Belongs to the pentaxin family.

Background :

C Reactive Protein (CRP) is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is composed of 5 identical, 21,500-molecular weight subunits. CRP mediates activities associated with preimmune nonspecific host resistance. CRP shows the strongest association with cardiovascular events. It is detectable on the surface of about 4% of normal peripheral blood lymphocytes. Acute phase reactant CRP is produced in the liver.

Research Category :

Apoptosis, Atherosclerosis, Cardiovascular, Chromatin Binding Proteins, Complement, DNA / RNA Binding, Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, Macrophage / Inflamm., Metabolism, Vascular Inflammation