Human FSTL1/Tsc 36 ELISA Kit PicoKine® | Boster EK0965 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human FSTL1/Tsc 36 ELISA Kit PicoKine®

catalog :

EK0965

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0965

Product Name :

Human FSTL1/Tsc 36 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human FSTL1/Tsc 36 ELISA Kit PicoKine® (96 Tests). Quantitate Human FSTL1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10 pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

FSTL1

Uniprot ID :

Q12841

Immunogen :

Expression system for standard: NS0; Immunogen sequence: M1-I308

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

312 pg/ml - 20,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Follistatin-related protein 1

Synonyms :

Follistatin-related protein 1;Follistatin-like protein 1;FSTL1;FRP;

Protein Name :

Follistatin-related protein 1

Molecular Weight :

34986 MW

Protein Function :

May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin (By similarity).

Subcellular Localization :

Secreted .

Tissue Specificity :

Overexpressed in synovial tissues from rheumatoid arthritis.

Sequence Similarities :

Contains 2 EF-hand domains.

Background :

Follistatin-related protein 1, also called FSTL1 or FRP is a protein that in humans is encoded by the FSTL1 gene. FSTL1 gene is mapped to chromosome 3q13.33 based on an alignment of FSTL1 sequence with the genomic sequence (GRCh37). This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis. This gene may modulate the action of some growth factors on cell proliferation and differentiation. It was suggested that fibroblast-secreted FSTL1 acts on macrophages to increase TNF and IL1B production and IL6 activity.

Research Category :

Atherosclerosis, Cardiovascular, Cell Biology, Cell Cycle, Cell Differentiation