Human IGFBP6 ELISA Kit PicoKine® | Boster EK0962 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human IGFBP6 ELISA Kit PicoKine®

catalog :

EK0962

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0962

Product Name :

Human IGFBP6 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human IGFBP6 ELISA Kit PicoKine® (96 Tests). Quantitate Human IGFBP6 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

IGFBP6

Uniprot ID :

P24592

Immunogen :

Expression system for standard: NS0; Immunogen sequence: A25-G240

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Insulin-like growth factor-binding protein 6

Synonyms :

Insulin-like growth factor-binding protein 6;IBP-6;IGF-binding protein 6;IGFBP-6;IGFBP6;IBP6;

Protein Name :

Insulin-like growth factor-binding protein 6

Molecular Weight :

25322 MW

Protein Function :

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Subcellular Localization :

Secreted.

Sequence Similarities :

Contains 1 IGFBP N-terminal domain.

Background :

Insulin-like growth factor-binding protein 6 (IGFBP6) is a protein that in humans is encoded by the IGFBP6 gene. The IGFBP6 gene is mapped to chromosome 12. In all, it has contained 216 amino acid protein with a calculated molecular mass of 22,847, The human keratinocyte cell line HaCat secretes IGFBP6 as an autocrine growth inhibitor. Recombinant IGFBP6 was also shown to inhibit growth of HaCat cells and other keratinocyte cell lines.

Research Category :

Growth Factors/Hormones, Lipid Signaling, Signal Transduction, Signaling Pathway