Human EPCR ELISA Kit PicoKine® | Boster EK0957 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human EPCR ELISA Kit PicoKine®

catalog :

EK0957

quantity :

96 wells/kit, with removable strips.

price :

399 USD

more info or order :

Boster product webpage

citations: 2

Reference
Lattenist L, Kers J, Claessen N, ten Berge I, Bemelman F, Florquin S, et al. Renal and urinary levels of endothelial protein C receptor correlate with acute renal allograft rejection. PLoS ONE. 2013;8:e64994 pubmed publisher
Chen X, Tian L, Li M, Jin W, Zhang H, Zheng C. Relationship between endothelial cell protein C receptor gene 6936A/G polymorphisms and deep venous thrombosis. Chin Med J (Engl). 2011;124:72-5 pubmed

image

image 1 :

Human EPCR PicoKine ELISA Kit standard curve

product information

SKU :

EK0957

Product Name :

Human EPCR ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

399 USD

Description :

Human EPCR ELISA Kit PicoKine® (96 Tests). Quantitate Human PROCR in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

PROCR

Uniprot ID :

Q9UNN8

Immunogen :

Expression system for standard: NS0; Immunogen sequence: S18-S210

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

312 pg/ml - 20,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Endothelial protein C receptor

Synonyms :

Endothelial protein C receptor;Activated protein C receptor;APC receptor;Endothelial cell protein C receptor;CD201;PROCR;EPCR;

Protein Name :

Endothelial protein C receptor

Molecular Weight :

26671 MW

Protein Function :

Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.

Subcellular Localization :

Membrane; Single-pass type I membrane protein.

Tissue Specificity :

Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney.

Background :

Endothelial protein C receptor (EPCR) also known as CCCA or PROCR is a protein that in humans is encoded by the PROCR gene. PRPCR gene is mapped to 20q11.2 by radiation hybrid analysis and FISH. The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.

Research Category :

Cardiovascular, Hematopoietic Progenitors, Stem Cells, Vasculature

more info or order :

Boster product webpage