Pig porcine Endothelin 1/EDN1 ELISA Kit PicoKine® | Boster EK0945-PO product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Pig porcine Endothelin 1/EDN1 ELISA Kit PicoKine®

catalog :

EK0945-PO

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 3

Reference
Jankowska Lech I, Terelak Borys B, Grabska Liberek I, Palasik W, Bik W, WoliÅ„ska Witort E. Decreased endothelin-1 plasma levels in multiple sclerosis patients: a possible factor of vascular dysregulation?. Med Sci Monit. 2015;21:1066-71 pubmed publisher
Groesdonk H, Raffel M, Speer T, Bomberg H, Schmied W, Klingele M, et al. Elevated endothelin-1 level is a risk factor for nonocclusive mesenteric ischemia. J Thorac Cardiovasc Surg. 2015;149:1436-42.e2 pubmed publisher
Wang G, Hu S, Sun J. [Effects of carvedilol on circulating levels of endothelin and von Willebrand factor in patients with unstable angina pectoris]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2002;31:340-343 pubmed

product information

SKU :

EK0945-PO

Product Name :

Pig porcine Endothelin 1/EDN1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Pig porcine Endothelin 1/EDN1 ELISA Kit PicoKine® (96 Tests). Quantitate Pig EDN1 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 0.5pg/ml.

Reactivity :

Pig

Application :

ELISA

Gene Name :

EDN1

Uniprot ID :

P09558

Immunogen :

Expression system for standard: pig porcine peptide; Immunogen sequence: C53-W73

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

3.9 pg/ml - 250 pg/ml

Sensitivity :

<0.5 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Endothelin-1

Synonyms :

Endothelin-1;Preproendothelin-1;PPET1;Endothelin-1;ET-1;Big endothelin-1;EDN1;

Protein Name :

Endothelin-1

Molecular Weight :

24425 MW

Protein Function :

Endothelins are endothelium-derived vasoconstrictor peptides.

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Sequence Similarities :

Belongs to the endothelin/sarafotoxin family.

Background :

The endothelins is a family of structurally and pharmacologically distinct peptides, which has been identified and sequenced in humans. Three isoforms of Pig porcine endothelin have been identified: endothelin-1, -2, and -3. Endothelin-1 is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis. Endothelins are implicated in vascular diseases of several organ systems, including the heart, general circulation and brain. Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure (hypertension) and heart disease.

Research Category :

Cancer, Cancer Metabolism, Cardiovascular, Growth Factors/Hormones, Metabolism, Metabolism Processes, Pathways And Processes, Response To Hypoxia, Signal Transduction, Vasculature

more info or order :

Boster product webpage