Human ICAM-3 / CD50 ELISA Kit PicoKine® | Boster EK0940 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human ICAM-3 / CD50 ELISA Kit PicoKine®

catalog :

EK0940

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0940

Product Name :

Human ICAM-3 / CD50 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human ICAM-3 / CD50 ELISA Kit PicoKine® (96 Tests). Quantitate Human ICAM3 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

ICAM3

Uniprot ID :

P32942

Immunogen :

Expression system for standard: NS0; Immunogen sequence: Q30-H485; homodimer

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Intercellular adhesion molecule 3

Synonyms :

Intercellular adhesion molecule 3;ICAM-3;CDw50;ICAM-R;CD50;ICAM3;

Protein Name :

Intercellular adhesion molecule 3

Molecular Weight :

59541 MW

Protein Function :

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2.

Subcellular Localization :

Membrane; Single-pass type I membrane protein.

Sequence Similarities :

Belongs to the immunoglobulin superfamily. ICAM family.

Background :

Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a human gene. The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. ICAM3 is closely related to ICAM1, consists of 5 immunoglobulin domains, and binds LFA1 through its 2 N-terminal domains. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM3 has been shown to interact with EZR and Moesin.

Research Category :

Adapters, Cell Type Markers, Immunology, Protein Phosphorylation, Signal Transduction, Transmembrane