Rat sL-Selectin ELISA Kit PicoKine® | Boster EK0937 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat sL-Selectin ELISA Kit PicoKine®

catalog :

EK0937

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0937

Product Name :

Rat sL-Selectin ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Rat sL-Selectin ELISA Kit PicoKine® (96 Tests). Quantitate Rat SELL in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 20pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

SELL

Uniprot ID :

Q63762

Immunogen :

Expression system for standard: NS0; Immunogen sequence: W39-N332

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

625 pg/ml - 40,000 pg/ml

Sensitivity :

<20 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

L-selectin

Synonyms :

L-selectin ;Sell ;rCG_45999 ;

Protein Name :

L-selectin

Molecular Weight :

42471 MW

Protein Function :

Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.

Sequence Similarities :

Belongs to the selectin/LECAM family.

Background :

L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17.SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins.1 L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point2.

Research Category :

Adaptive Immunity, Cardiovascular, Hematopoietic Progenitors, Immunology, Lymphoid, Myeloid, Stem Cells, T Cells, T Lymphocytic Lineage