Human IL-22/Interleukin-22 ELISA Kit PicoKine® | Boster EK0933 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human IL-22/Interleukin-22 ELISA Kit PicoKine®

catalog :

EK0933

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Ruggeri R, Minciullo P, Saitta S, Giovinazzo S, Certo R, CampennÃ¬ A, et al. Serum interleukin-22 (IL-22) is increased in the early stage of Hashimoto's thyroiditis compared to non-autoimmune thyroid disease and healthy controls. Hormones (Athens). 2014;13:338-44 pubmed publisher

image

image 1 :

Human IL-22 PicoKine ELISA Kit standard curve

product information

SKU :

EK0933

Product Name :

Human IL-22/Interleukin-22 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human IL-22 ELISA Kit PicoKine® (96 Tests). Quantitate Human IL22 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

IL22

Uniprot ID :

Q9GZX6

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: A34-I179

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Interleukin-22

Synonyms :

Interleukin-22;IL-22;Cytokine Zcyto18;IL-10-related T-cell-derived-inducible factor;IL-TIF;IL22;ILTIF, ZCYTO18;UNQ3099/PRO10096;

Protein Name :

Interleukin-22

Molecular Weight :

20011 MW

Protein Function :

Cytokine that contributes to the inflammatory response in vivo.

Subcellular Localization :

Secreted.

Sequence Similarities :

Belongs to the IL-10 family.

Background :

Interleukin-22 (IL-22), also known as ILTIF, is protein that in humans is encoded by the IL22 gene. IL-22 a member of a group of cytokines called the IL-10 family or IL-10 superfamily a class of potent mediators of cellular inflammatory responses. Using FISH, the IL22 gene is mapped to chromosome 12q15, close to the IFNG and the herpesvirus saimiri-induced AK155 genes. IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. In some contexts, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by the often co-expressed cytokine IL-17A.

Research Category :

Adapters, Cytokines, Immunology, Innate Immunity, Interleukins, Macrophage / Inflamm., Signal Transduction, Transmembrane

more info or order :

Boster product webpage