Mouse DKK-1 ELISA Kit PicoKine® | Boster EK0925 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse DKK-1 ELISA Kit PicoKine®

catalog :

EK0925

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Yang Z, Huang X, Zhang J, You K, Xiong Y, Fang J, et al. Hepatic DKK1-driven steatosis is CD36 dependent. Life Sci Alliance. 2023;6: pubmed publisher

product information

SKU :

EK0925

Product Name :

Mouse DKK-1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Mouse DKK-1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Dkk1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 15pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

DKK1

Uniprot ID :

O54908

Immunogen :

Expression system for standard: CHO; Immunogen sequence: S30-H272

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

46.9 pg/ml - 3,000 pg/ml

Sensitivity :

<15 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Dickkopf-related protein 1

Synonyms :

Dickkopf-related protein 1;Dickkopf-1;Dkk-1;mDkk-1;Dkk1;

Protein Name :

Dickkopf-related protein 1

Molecular Weight :

29298 MW

Protein Function :

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6.

Subcellular Localization :

Secreted.

Background :

Dickkopf-related protein 1 is a protein that in humans is encoded by the DKK1 gene, which was mapped to chromosome 10q11.2. This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow, plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

Research Category :

Cardiovascular, Developmental Biology, Embryogenesis, Immunology, Secreted, Signaling Pathways, Stem Cells

more info or order :

Boster product webpage