Mouse CD23/FCER2 ELISA Kit PicoKine® | Boster EK0924 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse CD23/FCER2 ELISA Kit PicoKine®

catalog :

EK0924

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0924

Product Name :

Mouse CD23/FCER2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse CD23/FCER2 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Fcer2 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 15pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

Fcer2

Uniprot ID :

P20693

Immunogen :

Expression system for standard: NS0; Immunogen sequence: E50-P331

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<15 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Low affinity immunoglobulin epsilon Fc receptor

Synonyms :

Low affinity immunoglobulin epsilon Fc receptor;Fc-epsilon-RII;Lymphocyte IgE receptor;CD23;Fcer2;Fcer2a;

Protein Name :

Low affinity immunoglobulin epsilon Fc receptor

Molecular Weight :

37648 MW

Protein Function :

Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).

Subcellular Localization :

Cell membrane ; Single-pass type II membrane protein . Cell membrane ; Lipid-anchor .

Background :

CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the CD23 gene was assigned to 19p13.3. And CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.

Research Category :

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunoglobulins, Immunology, Lymphoid, Receptors, Stem Cells