Human SCGB1A1/uteroglobin ELISA Kit PicoKine® | Boster EK0922 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human SCGB1A1/uteroglobin ELISA Kit PicoKine®

catalog :

EK0922

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Loughran Fowlds A, Lin J, Oei J, Michalowski J, Henry R, Lui K. Early postnatal surge of serum Clara cell secretory protein in newborn infants. Neonatology. 2012;101:125-31 pubmed publisher

image

image 1 :

Human SCGB1A1/uteroglobin PicoKine ELISA Kit standard curve

product information

SKU :

EK0922

Product Name :

Human SCGB1A1/uteroglobin ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human SCGB1A1/uteroglobin ELISA Kit PicoKine® (96 Tests). Quantitate Human SCGB1A1 in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk. Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

SCGB1A1

Uniprot ID :

P11684

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: E22-N91

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA), saliva, urine and human milk

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Uteroglobin

Synonyms :

Uteroglobin;Clara cell phospholipid-binding protein;CCPBP;Clara cells 10 kDa secretory protein;CC10;Secretoglobin family 1A member 1;Urinary protein 1;UP-1;UP1;Urine protein 1;SCGB1A1;CC10, CCSP, UGB;

Protein Name :

Uteroglobin

Molecular Weight :

9994 MW

Protein Function :

Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.

Subcellular Localization :

Secreted.

Tissue Specificity :

Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways).

Background :

SCGB1A1 (secretoglobin family 1A member 1) also known as Uteroglobin is a protein that in humans is encoded by the SCGB1A1 gene. SCGB1A1 is the founding member of the secretoglobin family of small, secreted, disulfide-bridged dimeric proteins found only in mammals. This protein is specifically expressed in Clara cells in the lungs. Numerous studies demonstrated that UG is a multifunctional protein with antiinflammatory/ immunomodulatory properties. It inhibits soluble phospholipase A (2) activity and binds and perhaps sequesters hydrophobic ligands such as progesterone, retinols, polychlorinated biphenyls, phospholipids, and prostaglandins. In addition to its antiinflammatory activities, UG manifests antichemotactic, antiallergic, antitumorigenic, and embryonic growth-stimulatory activities.

Research Category :

Immunoglobulins, Immunology

more info or order :

Boster product webpage