Human CD23/FCER2 ELISA Kit PicoKine® | Boster EK0912 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human CD23/FCER2 ELISA Kit PicoKine®

catalog :

EK0912

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0912

Product Name :

Human CD23/FCER2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human CD23/FCER2 ELISA Kit PicoKine® (96 Tests). Quantitate Human FCER2 in cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

FCER2

Uniprot ID :

K3W4U1

Immunogen :

Expression system for standard: NS0; Immunogen sequence: D48-S321

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA) and urine

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Fc fragment of IgE, low affinity II, receptor for (CD23)

Synonyms :

Low affinity immunoglobulin epsilon Fc receptor ;FCER2 ;

Protein Name :

Low affinity immunoglobulin epsilon Fc receptor

Molecular Weight :

36299 MW

Sequence Similarities :

Contains C-type lectin domain.

Background :

CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.

Research Category :

Receptors, Stem Cells