ELISA/assay

Human KIM1 / TIM-1 ELISA Kit PicoKine®

EK0883

1

Human KIM1 / TIM-1 ELISA Kit PicoKine®

human-kim1-picokine-trade-elisa-kit-ek0883-boster

Picokine ELISA Kits

HAVCR1

380

31.2 pg/ml - 2,000 pg/ml

Human KIM1 / TIM-1 ELISA Kit PicoKine (96 Tests). Quantitate Human HAVCR1 in cell culture supernatants, cell lysates, serum, plasma (heparin, EDTA) and urine. Sensitivity: 2pg/ml.

Human KIM1 / TIM-1 ELISA Kit PicoKine (96 Tests). Quantitate Human HAVCR1 in cell culture supernatants, cell lysates, serum, plasma (heparin, EDTA) and urine. Sensitivity: 2pg/ml.

96 wells/kit, with removable strips.

Q96D42

Expression system for standard: NS0; Immunogen sequence: S21-T288

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

There is no detectable cross-reactivity with other relevant proteins.

<2 pg/ml

10 ng/tube

cell culture supernatants, cell lysates, serum, plasma (heparin, EDTA) and urine.

Dilution ratio of 1:1, concentration in serum is NO-30pg/ml

ELISA

Human

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Human KIM1 PicoKine ELISA Kit standard curve

Concentration (pg/ml) 0 31.2 62.5 125 250 500 1000 2000 O.D. 0.037 0.075 0.135 0.193 0.305 0.644 1.139 1.933

5/10/14 9:17

3/2/22 2:54

Human KIM1 / TIM-1 ELISA Kit Price PicoKine® BosterBio

Human KIM1 ELISA Kit PicoKine, Bosterbio High Sensitivity

Human KIM1 / TIM-1 ELISA Kit PicoKine (96 Tests). Quantitate Human HAVCR1 in cell culture supernatants, cell lysates, serum, plasma (heparin, EDTA) and urine. Sensitivity: 2pg/ml.

100

heparin or EDTA

2,000 pg/ml, 1,000 pg/ml, 500 pg/ml, 250 pg/ml, 125 pg/ml, 62.5 pg/ml, 31.2 pg/ml

KIM1 (TIM-1), also known as Hepatitis A virus cellular receptor 1, is a protein that in Rats is encoded by the HAVCR1 gene. Infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV led to conclude that the protein is indeed a receptor for the virus. Immunofluorescence microscopy demonstrated internalization of HAV by dog cells expressing HAVCR1. Using a monoclonal antibody to Rat Tim1, Tim1 was expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. By homology of synteny with the Rat Tim1 gene and database analysis, the HAVCR1 gene was mapped to 5q33.2.

Adaptive Immunity,Host Virus Interaction,Immune System Diseases,Immunology,Interspecies Interaction,Microbiology,Non-Cd,T Cells

Hepatitis A virus cellular receptor 1;HAVcr-1;Kidney injury molecule 1;KIM-1;T-cell immunoglobulin and mucin domain-containing protein 1;TIMD-1;T-cell immunoglobulin mucin receptor 1;TIM;TIM-1;T-cell membrane protein 1;HAVCR1;KIM1, TIM1, TIMD1;

Hepatitis A virus cellular receptor 1

38720 MW

May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair.

Membrane ; Single-pass type I membrane protein .

Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses.

Hepatitis A virus cellular receptor 1

Belongs to the immunoglobulin superfamily. TIM family.

Intra-Assay Precision Inter-Assay Precision Sample 1 2 3 1 2 3 n 16 16 16 24 24 24 Mean (pg/ml) 92 215 880 93 208 802 Standard deviation 5.42 9.24 39.6 5.48 11.02 40.1 CV (%) 4.5% 4.3% 4.5% 5.9% 5.3% 5%

Lots Lot 1 (pg/ml) Lot 2 (pg/ml) Lot 3 (pg/ml) Lot 4 (pg/ml) Mean (pg/ml) Standard Deviation CV (%) Sample 1 92 93 93 91 92 0.82 0.8% Sample 2 215 235 212 211 218 9.78 4.4% Sample 3 880 798 777 920 843 58.47 6.9% *number of samples for each test n=16.

15-25min

polyclonal antibody from goat polyclonal antibody from goat

21279810

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