Human NOV/CCN3 ELISA Kit PicoKine® | Boster EK0833 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human NOV/CCN3 ELISA Kit PicoKine®

catalog :

EK0833

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0833

Product Name :

Human NOV/CCN3 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human NOV/CCN3 ELISA Kit PicoKine® (96 Tests). Quantitate Human CCN3 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 2pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

NOV

Uniprot ID :

P48745

Immunogen :

Expression system for standard: NS0; Immunogen sequence: T32-M357

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<2 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Protein NOV homolog

Synonyms :

Protein NOV homolog;NovH;CCN family member 3;Insulin-like growth factor-binding protein 9;IBP-9;IGF-binding protein 9;IGFBP-9;Nephroblastoma-overexpressed gene protein homolog;NOV;CCN3, IGFBP9, NOVH;

Protein Name :

Protein NOV homolog

Molecular Weight :

39162 MW

Protein Function :

Immediate-early protein likely to play a role in cell growth regulation.

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed in bone marrow, thymic cells and nephroblastoma. Increased expression in Wilms tumor of the stromal type.

Sequence Similarities :

Belongs to the CCN family.

Background :

NOV (nephroblastoma overexpressed), also known as CCN3, is a matricellular protein that in humans is encoded by the NOV gene. The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. This gene is mapped to 8q24.12. NOV is a potentially useful marker for the diagnosis of adrenal gland diseases, malignant adrenocortical tumors, multiple sclerosis and so on. Moreover, reduced expression of NOV in ACTs may play an important role in the process of childhood ACT tumorigenesis. Though studying, it identified Nov as a regulator of human hematopoietic stem or progenitor cells.