Rat CXCL5/LIX/ENA-78 ELISA Kit PicoKine® | Boster EK0823 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat CXCL5/LIX/ENA-78 ELISA Kit PicoKine®

catalog :

EK0823

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0823

Product Name :

Rat CXCL5/LIX/ENA-78 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Rat CXCL5/LIX/ENA-78 ELISA Kit PicoKine® (96 Tests). Quantitate Rat Cxcl5 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 1pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

Cxcl5

Uniprot ID :

P97885

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: A38-Q130

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<1 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

C-X-C motif chemokine 5

Synonyms :

C-X-C motif chemokine 5;Cytokine LIX;Small-inducible cytokine B5;Cxcl5;Scyb5;

Protein Name :

C-X-C motif chemokine 5

Molecular Weight :

14263 MW

Protein Function :

May participate in the recruitment of inflammatory cells by injured or infected tissue.

Subcellular Localization :

Secreted.

Background :

C-X-C motif chemokine 5 is a protein that in humans encoded by the CXCL5 gene. The protein encoded by this gene, CXCL5 is a small cytokine belonging to the CXC chemokine family that is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). It is produced following stimulation of cells with the inflammatory cytokines interleukin-1or tumor necrosis factor-alpha. Expression of CXCL5 has also been observed in eosinophils, and can be inhibited with the type II interferon IFN-gamma. This chemokine stimulates the chemotaxis of neutrophils possessing angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2. The gene for CXCL5 is encoded on four exons and is located on humanchromosome 4 amongst several other CXC chemokine genes. CXCL5 has been implicated in connective tissue remodeling. CXCL5 plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which can be utilized to understand more about pain in other inflammatory conditions like arthritis and cystitis.

Research Category :

Atherosclerosis, Cardiovascular, Chemokines, Immunology, Innate Immunity, Macrophage / Inflamm., Vascular Inflammation