ELISA/assay

Human MBL2/MPB-C ELISA Kit PicoKine®

EK0805

1

Human MBL2/MPB-C ELISA Kit PicoKine®

human-mbp-c-mbl2-picokine-trade-elisa-kit-ek0805-boster

Picokine ELISA Kits

MBL2

369

312 pg/ml - 20,000 pg/ml

Human MBL2/MPB-C ELISA Kit PicoKine (96 Tests). Quantitate Human MBL2 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Human MBL2/MPB-C ELISA Kit PicoKine (96 Tests). Quantitate Human MBL2 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

96 wells/kit, with removable strips.

P11226

Expression system for standard: NS0; Immunogen sequence: E21-I248

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

There is no detectable cross-reactivity with other relevant proteins.

<10 pg/ml

20 ng/tube

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

ELISA

Human

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Human MBP-C/MBL2 PicoKine ELISA Kit standard curve

Concentration (pg/ml) 0 312 625 1250 2500 5000 10000 20000 O.D. 0.006 0.158 0.306 0.538 0.807 1.261 1.647 1.940

10/23/14 19:53

3/2/22 2:55

Human MBL2/MPB-C ELISA Kit Price PicoKine® BosterBio

Human MBP-C/MBL2 ELISA Kit, MBP C, MBP ELISA, Bosterbio High Sensitivity

Human MBL2/MPB-C ELISA Kit PicoKine (96 Tests). Quantitate Human MBL2 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

100

heparin or EDTA

20,000 pg/ml, 10,000 pg/ml, 5,000 pg/ml, 2,500 pg/ml, 1,250 pg/ml, 625 pg/ml, 312 pg/ml

MBL2, also called mannose-binding lectin (protein C) 2, soluble or Mannose-binding lectin (MBL) is a lectin that is instrumental in innate immunity. MBL2 is mapped to chromosome 10q11.2-q21. It belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL2 recognizes carbohydrate patterns, found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa and fungi. Binding MBL2 to a micro-organism results in activation of the lectin pathway of the complement system. Another important function of MBL2 is that this molecule binds senescent and apoptotic cells and enhances engulfment of whole, intact apoptotic cells, as well as cell debris by phagocytes.

Complement,Immunology,Innate Immunity

Mannose-binding protein C;MBP-C;Collectin-1;MBP1;Mannan-binding protein;Mannose-binding lectin;MBL2;COLEC1, MBL;

Mannose-binding protein C

26144 MW

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.

Secreted .

Plasma protein produced mainly in the liver.

Mannose-binding protein C

Contains 1 C-type lectin domain.

Intra-Assay Precision Inter-Assay Precision Sample 1 2 3 1 2 3 n 16 16 16 24 24 24 Mean (pg/ml) 479 2854 8702 458 2785 8839 Standard deviation 27.3 129.09 661.35 34.35 147.6 742.47 CV (%) 5.7% 4.4% 7.6% 7.5% 5.3% 8.4%

Lots Lot 1 (pg/ml) Lot 2 (pg/ml) Lot 3 (pg/ml) Lot 4 (pg/ml) Mean (pg/ml) Standard Deviation CV (%) Sample 1 479 546 475 475 493 30.21 6.1% Sample 2 2934 2910 2938 2814 2899 50.22 1.7% Sample 3 8702 9816 8527 9384 9107 519.57 5.7% *number of samples for each test n=16.

15-25min

monoclonal antibody from mouse polyclonal antibody from goat

25709904

elisa-kits