Human IL-17RB ELISA Kit PicoKine® | Boster EK0785 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human IL-17RB ELISA Kit PicoKine®

catalog :

EK0785

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0785

Product Name :

Human IL-17RB ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human IL-17RB ELISA Kit PicoKine® (96 Tests). Quantitate Human IL17RB in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

IL17RB

Uniprot ID :

Q9NRM6

Immunogen :

Expression system for standard: NS0; Immunogen sequence: R18-K286

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Interleukin-17 receptor B

Synonyms :

Interleukin-17 receptor B;IL-17 receptor B;IL-17RB;Cytokine receptor-like 4;IL-17 receptor homolog 1;IL-17Rh1;IL17Rh1;Interleukin-17B receptor;IL-17B receptor;IL17RB;CRL4, EVI27, IL17BR;UNQ2501/PRO19612;

Protein Name :

Interleukin-17 receptor B

Molecular Weight :

55885 MW

Protein Function :

Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.

Subcellular Localization :

Isoform 1: Cell membrane; Single-pass type I membrane protein.

Tissue Specificity :

Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.

Sequence Similarities :

Contains 1 SEFIR domain.

Background :

IL17RB, also known as CRL4, is a protein that in humans is encoded by the IL17RB gene. It is located on 3p21.1. IL17RB is produced by activated T cells exhibiting proinflammatory activities. The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E (IL25), but does not bind to IL17 (A) or IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. And it may play a role in controlling the growth and/or differentiation of hematopoietic cells.

Research Category :

Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Cytokines, Immunology, Innate Immunity, Interleukins, Macrophage / Inflamm.