Mouse IL-1RA/IL1RN ELISA Kit PicoKine® | Boster EK0783 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse IL-1RA/IL1RN ELISA Kit PicoKine®

catalog :

EK0783

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0783

Product Name :

Mouse IL-1RA/IL1RN ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse IL-1RA/IL1RN ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Il1rn in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

IL1RN

Uniprot ID :

P25085

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: R27-Q178

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Interleukin-1 receptor antagonist protein

Synonyms :

Interleukin-1 receptor antagonist protein;IL-1RN;IL-1ra;IRAP;IL1 inhibitor;Il1rn;Il-1ra;

Protein Name :

Interleukin-1 receptor antagonist protein

Molecular Weight :

20274 MW

Protein Function :

Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.

Subcellular Localization :

Isoform 1: Secreted.

Background :

The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The human IL1RN gene was localized to the long arm of chromosome 2 at band 2q14.2 by fluorescence in situ hybridization. IL-1RA is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses.

Research Category :

Cytokines, Immunology, Innate Immunity, Interleukins