Human HAI-2/SPINT2 ELISA Kit PicoKine® | Boster EK0773 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human HAI-2/SPINT2 ELISA Kit PicoKine®

catalog :

EK0773

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0773

Product Name :

Human HAI-2/SPINT2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human HAI-2/SPINT2 ELISA Kit PicoKine® (96 Tests). Quantitate Human SPINT2 in cell culture supernatants, serum, plasma (heparin, EDTA) and cell lysates. Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

SPINT2

Uniprot ID :

O43291

Immunogen :

Expression system for standard: NS0; Immunogen sequence: M1-K197

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA) and cell lysate

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Kunitz-type protease inhibitor 2

Synonyms :

Kunitz-type protease inhibitor 2;Hepatocyte growth factor activator inhibitor type 2;HAI-2;Placental bikunin;SPINT2;HAI2, KOP;

Protein Name :

Kunitz-type protease inhibitor 2

Molecular Weight :

28228 MW

Protein Function :

Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.

Subcellular Localization :

Membrane ; Single-pass type I membrane protein .

Tissue Specificity :

Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea.

Background :

Kunitz-type protease inhibitor 2 is an enzyme inhibitor that in humans is encoded by the SPINT2 gene. This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. And this gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Category :

Cell Biology, Developmental Biology, Neurogenesis, Neurology Process, Neuroscience, Protease Inhibitors, Proteolysis / Ubiquitin, Reproduction