Human TNFRSF18/GITR ELISA Kit PicoKine¬Æ | Boster EK0768 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human TNFRSF18/GITR ELISA Kit PicoKine¬Æ

catalog :

EK0768

more info or order :

Boster product webpage

citations: 1

Reference
Gan X, Feng X, Gu L, Tan W, Sun X, Lv C, et al. Correlation of increased blood levels of GITR and GITRL with disease severity in patients with primary Sjögren's syndrome. Clin Dev Immunol. 2013;2013:340751 pubmed publisher

image

image 1 :

Human TNFRSF18/GITR PicoKine ELISA Kit standard curve

product information

sku :

EK0768

status :

name :

Human TNFRSF18/GITR ELISA Kit PicoKine¬Æ

url key :

human-tnfrsf18-gitr-picokine-trade-elisa-kit-ek0768-boster

product category :

Picokine ELISA Kits

gene name :

TNFRSF18

price :

369

assay range :

62.5 pg/ml - 4,000 pg/ml

description :

Human TNFRSF18/GITR ELISA Kit PicoKine (96 Tests). Quantitate Human TNFRSF18 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

short description :

Human TNFRSF18/GITR ELISA Kit PicoKine (96 Tests). Quantitate Human TNFRSF18 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

size :

96 wells/kit, with removable strips.

uniprot id :

Q9Y5U5

immunogen :

Expression system for standard: NS0; Immunogen sequence: Q26-E161

storage :

Store at 4¬∞C for 6 months, at -20¬∞C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

cross reactivity :

There is no detectable cross-reactivity with other relevant proteins.

sensitivity :

<10 pg/ml

kit components :

10 ng/tube

sample type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

applications :

ELISA

reactivity :

Human

images :

/antibody/ek0768-2-ELISA-human-tnfrsf18-gitr-picokine-elisa-kit.jpg

image labels :

Human TNFRSF18/GITR PicoKine ELISA Kit standard curve

sample data :

Concentration (pg/ml) 0 62.5 125 250 500 1000 2000 4000 O.D. 0.031 0.095 0.175 0.299 0.596 1.008 1.651 2.111

created at :

5/13/14 14:17

updated at :

3/2/22 2:54

description before attributes :

Featured Product . Fast ELISA kit now available: Boster is proud to announce the newest Picokine Fast ELISA kits. Now you can perform what used to be 4+ hour ELISA assay in under 1.5 hours. Available for Human TNFRSF18/GITR PicoKine Fast ELISA Kit and many others.

meta title :

Human TNFRSF18/GITR ELISA Kit Price PicoKine¬Æ BosterBio

meta keyword :

Human TNFRSF18/GITR ELISA Kit, AITR, GITR ELISA Kit

meta description :

Human TNFRSF18/GITR ELISA Kit PicoKine (96 Tests). Quantitate Human TNFRSF18 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

rating value :

100

anticoagulant :

heparin or EDTA

assay procedure step 1 :

4,000 pg/ml, 2,000 pg/ml, 1,000 pg/ml, 500 pg/ml, 250 pg/ml, 125 pg/ml, 62.5 pg/ml

background :

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. This gene is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

research category :

Adaptive Immunity,Cancer,Cytokines,Growth Factors,Growth Factors/Hormones,Immunology,Innate Immunity,Signal Transduction

synonyms :

Tumor necrosis factor receptor superfamily member 18;Activation-inducible TNFR family receptor;Glucocorticoid-induced TNFR-related protein;CD357;TNFRSF18;AITR, GITR;UNQ319/PRO364;

gene full name :

Tumor necrosis factor receptor superfamily member 18

molecular weight :

26000 MW

protein function :

Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

subcellular localization :

Isoform 1: Cell membrane; Single-pass type I membrane protein.

tissue specificity :

Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.

protein name :

Tumor necrosis factor receptor superfamily member 18

intra inter assay cv :

Intra-Assay Precision Inter-Assay Precision Sample 1 2 3 1 2 3 n 16 16 16 24 24 24 Mean (pg/ml) 135 705 1313 138 657 1352 Standard deviation 7.15 40.89 101.1 8.83 42.7 108.16 CV (%) 5.3% 5.8% 7.7% 6.4% 6.5% 8%

reproducibility :

Lots Lot 1 (pg/ml) Lot 2 (pg/ml) Lot 3 (pg/ml) Lot 4 (pg/ml) Mean (pg/ml) Standard Deviation CV (%) Sample 1 135 136 127 144 135 6.02 4.4% Sample 2 705 808 735 671 729 50.53 6.9% Sample 3 1313 1243 1354 1475 1346 84.26 6.2% *number of samples for each test n=16.

tmb incubation time :

15-25min

principle :

monoclonal antibody from mouse polyclonal antibody from goat

normal range citations :

23935647

template :

elisa-kits

more info or order :

Boster product webpage