Mouse ESM1/Endocan ELISA Kit PicoKine® | Boster EK0753 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse ESM1/Endocan ELISA Kit PicoKine®

catalog :

EK0753

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0753

Product Name :

Mouse ESM1/Endocan ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse ESM1/Endocan ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Esm1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

ESM1

Uniprot ID :

Q9QYY7

Immunogen :

Expression system for standard: NS0; Immunogen sequence: W20-R184

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

23.4 pg/ml - 1500 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Endothelial cell-specific molecule 1

Synonyms :

Endothelial cell-specific molecule 1;ESM-1;Esm1;

Protein Name :

Endothelial cell-specific molecule 1

Molecular Weight :

20043 MW

Protein Function :

Involved in angiogenesis; promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions (By similarity).

Subcellular Localization :

Secreted .

Background :

Endothelial cell-specific molecule 1, also known as Endocan, is a protein that in humans is encoded by the ESM1 gene. This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. ESM-1 has been described as a specific biomarker of tip cells during neoangiogenesis by independent teams. Its expression has been shown to be increase in presence of pro-angiogenic growth factors such as VEGF (vascular endothelial growth factor) or FGF-2 (fibroblast growth factor 2).

Research Category :

Cell Type Markers, Tags & Cell Markers