Mouse DAN/NBL1 ELISA Kit PicoKine® | Boster EK0747 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse DAN/NBL1 ELISA Kit PicoKine®

catalog :

EK0747

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0747

Product Name :

Mouse DAN/NBL1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse DAN/NBL1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Nbl1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

Nbl1

Uniprot ID :

Q61477

Immunogen :

Expression system for standard: NS0; Immunogen sequence: A17-D178

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Neuroblastoma suppressor of tumorigenicity 1

Synonyms :

Neuroblastoma suppressor of tumorigenicity 1;N03;Zinc finger protein DAN;Nbl1;Dan, Dana;

Protein Name :

Neuroblastoma suppressor of tumorigenicity 1

Molecular Weight :

19107 MW

Protein Function :

Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process.

Subcellular Localization :

Secreted .

Background :

Differential screening-selected gene aberrative in neuroblastoma (DAN) is a member of the DAN family of secreted glycoproteins that are putative BMP antagonists. The NBL1 gene, also known as DAN, is originally cloned from a normal rat fibroblast cDNA library by a differential screening method. The human DAN gene is mapped to chromosome 1p36.13-p36. It is found that the DAN gene possesses a tumor suppressive activity when overexpressed in v-src transformed cells.

Research Category :

Cancer, Growth Factors/Hormones, Oncoproteins/Suppressors, Signal Transduction, Tumor Suppressors