Human CXCL16 ELISA Kit PicoKine¬Æ | Boster EK0741 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human CXCL16 ELISA Kit PicoKine¬Æ

catalog :

EK0741

more info or order :

Boster product webpage

citations: 1

Reference
Ma A, Pan X, Xing Y, Wu M, Wang Y, Ma C. Elevation of serum CXCL16 level correlates well with atherosclerotic ischemic stroke. Arch Med Sci. 2014;10:47-52 pubmed publisher

image

image 1 :

Human CXCL16 PicoKine ELISA Kit standard curve

product information

sku :

EK0741

status :

name :

Human CXCL16 ELISA Kit PicoKine¬Æ

url key :

human-cxcl16-picokine-trade-elisa-kit-ek0741-boster

product category :

Picokine ELISA Kits

gene name :

CXCL16

price :

369

assay range :

93.7 pg/ml - 6,000 pg/ml

description :

Human CXCL16 ELISA Kit PicoKine (96 Tests). Quantitate Human CXCL16 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

short description :

Human CXCL16 ELISA Kit PicoKine (96 Tests). Quantitate Human CXCL16 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

size :

96 wells/kit, with removable strips.

uniprot id :

Q9H2A7

immunogen :

Expression system for standard: E.coli; Immunogen sequence: N49-P137

storage :

Store at 4¬∞C for 6 months, at -20¬∞C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

cross reactivity :

There is no detectable cross-reactivity with other relevant proteins.

sensitivity :

<10 pg/ml

kit components :

10 ng/tube

sample type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

application details :

Dilution ratio of 1:5, concentration in serum is around 2ng/ml

applications :

ELISA

reactivity :

Human

images :

/antibody/ek0741-2-ELISA-human-cxcl16-picokine-elisa-kit.jpg

image labels :

Human CXCL16 PicoKine ELISA Kit standard curve

sample data :

Concentration (pg/ml) 0 93.7 187.5 375 750 13000 3000 6000 O.D. 0.055 0.204 0.358 0.787 0.906 1.686 2.029 2.120

created at :

5/14/14 18:17

updated at :

3/2/22 2:54

meta title :

Human CXCL16 ELISA Kit Price PicoKine¬Æ BosterBio

meta keyword :

Human CXCL16 ELISA Kit, CXL16 ELISA Kit, Bosterbio High Sensitivity

meta description :

Human CXCL16 ELISA Kit PicoKine (96 Tests). Quantitate Human CXCL16 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

rating value :

100

anticoagulant :

heparin or EDTA

assay procedure step 1 :

6,000 pg/ml, 3,000 pg/ml, 1,500 pg/ml, 750 pg/ml, 375 pg/ml, 187.5 pg/ml, 93.7pg/m

background :

Chemokine (C-X-C motif) ligand 16 (CXCL16) is a small cytokine belonging to the CXC chemokine family. Larger than other chemokines (with 254 amino acids), CXCL16 is composed of a CXC chemokine domain, a mucin-like stalk, a transmembrane domain and a cytoplasmic tail containing a potential tyrosine phosphorylation site that may bind SH2. These are unusual features for a chemokine, and allow CXCL16 to be expressed as a cell surface bound molecule, as well as a soluble chemokine. CXCL16 is produced by dendritic cells found in the T cell zones of lymphoid organs, and by cells found in the red pulp of the spleen. Cells that bind and migrate in response to CXCL16 include several subsets of T cells, and natural killer T (NKT) cells. CXCL16 interacts with the chemokine receptorCXCR6, also known as Bonzo. The novel CXC-chemokine ligand 16 (CXCL16) functions as transmembrane adhesion molecule on the surface of APCs and as a soluble chemoattractant for activated T cells. Expression of CXCL16 is induced by the inflammatory cytokines IFN-gamma and TNF-alpha. The gene for human CXCL16 is located on chromosome 17.

competitor equivalent skus :

sc 27343 sc 27342 sc 376395 sc 27344 sc 398792 sc 514363

research category :

Chemokines,Immunology,Innate Immunity,Macrophage / Inflamm.

synonyms :

C-X-C motif chemokine 16;Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein;SR-PSOX;Small-inducible cytokine B16;Transmembrane chemokine CXCL16;CXCL16;SCYB16, SRPSOX;UNQ2759/PRO6714;

gene full name :

C-X-C motif chemokine 16

molecular weight :

27579 MW

protein function :

Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.

subcellular localization :

Cell membrane ; Single-pass type I membrane protein . Secreted. Also exists as a soluble form.

tissue specificity :

Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.

protein name :

C-X-C motif chemokine 16

sequence similarities :

Belongs to the intercrine alpha (chemokine CxC) family.

intra inter assay cv :

Intra-Assay Precision Inter-Assay Precision Sample 1 2 3 1 2 3 n 16 16 16 24 24 24 Mean (pg/ml) 122 725 2351 133 696 2150 Standard deviation 9.15 55.82 185.72 10.24 57.7%8 197.8 CV (%) 7.5% 7.7% 7.9% 7.7% 8% 9.2%

reproducibility :

Lots Lot 1 (pg/ml) Lot 2 (pg/ml) Lot 3 (pg/ml) Lot 4 (pg/ml) Mean (pg/ml) Standard Deviation CV (%) Sample 1 122 112 116 125 118 5.06 4.2% Sample 2 725 748 679 765 729 32.29 4.4% Sample 3 2351 2384 2122 2446 2325 122.47 5.2% *number of samples for each test n=16.

tmb incubation time :

15-25min

principle :

monoclonal antibody from mouse polyclonal antibody from goat

normal range citations :

24701213

template :

elisa-kits

more info or order :

Boster product webpage