ELISA/assay

Human CXCL11/I-TAC ELISA Kit PicoKine®

EK0737

1

Human CXCL11/I-TAC ELISA Kit PicoKine®

human-cxcl11-i-tac-picokine-trade-elisa-kit-ek0737-boster

Picokine ELISA Kits

CXCL11

369

31.2 pg/ml - 2,000 pg/ml

Human CXCL11/I-TAC ELISA Kit PicoKine (96 Tests). Quantitate Human CXCL11 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Human CXCL11/I-TAC ELISA Kit PicoKine (96 Tests). Quantitate Human CXCL11 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

96 wells/kit, with removable strips.

O14625

Expression system for standard: E.coli; Immunogen sequence: F22-F94

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

There is no detectable cross-reactivity with other relevant proteins.

<10 pg/ml

10 ng/tube

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

ELISA

Human

/e/k/ek0737.png

Human CXCL11/I-TAC PicoKine ELISA Kit standard curve

Concentration (pg/ml) 0 31.2 62.5 125 250 500 1000 2000 O.D. 0.045 0.111 0.147 0.255 0.562 1.089 2.019 2.379

5/14/14 18:17

3/2/22 2:54

Human CXCL11/I-TAC ELISA Kit Price PicoKine® BosterBio

Human CXCL11/I-TAC ELISA Kit, I TAC ELISA Kit, Bosterbio High Sensitivity

Human CXCL11/I-TAC ELISA Kit PicoKine (96 Tests). Quantitate Human CXCL11 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

98.3

heparin or EDTA

2,000 pg/ml, 1,000 pg/ml, 500 pg/ml, 250 pg/ml, 125 pg/ml, 62.5 pg/ml, 312 pg/ml

Chemokine (C-X-C motif) ligand 11 (CXCL11) is a small cytokine belonging to the CXC chemokine family that is also called Interferon-inducible T-cell alpha chemoattractant (I-TAC) and Interferon-gamma-inducible protein 9 (IP-9). By PCR analysis of somatic cell hybrids, the CXCL11 gene was mapped to chromosome 4, and using FISH, it was located to 4q21.2. The CXCL11 was strongly induced by IFNG and beta-interferon, but only weakly induced by alpha-interferon. Induction of CXCL11 required expression of STAT1. What's more, it found that monocyte chemotaxis occurs in response to recombinant CXCL11. RT-PCR analysis detected CXCL11 expression in brain tissue from a patient with AIDS dementia and a patient with multiple sclerosis but not in 2 controls.

Autoimmune,Chemokines,Immune System Diseases,Immunology,Innate Immunity,Neurodegenerative Disease,Neurology Process,Neuroscience

C-X-C motif chemokine 11;Beta-R1;H174;Interferon gamma-inducible protein 9;IP-9;Interferon-inducible T-cell alpha chemoattractant;I-TAC;Small-inducible cytokine B11;CXCL11;ITAC, SCYB11, SCYB9B;

C-X-C motif chemokine 11

10365 MW

Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.

Secreted.

High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.

C-X-C motif chemokine 11

Belongs to the intercrine alpha (chemokine CxC) family.

Intra-Assay Precision Inter-Assay Precision Sample 1 2 3 1 2 3 n 16 16 16 24 24 24 Mean (pg/ml) 107 712 1603 100 764 1565 Standard deviation 7.91 47.7 83.35 8.7 64.94 82.94 CV (%) 7.4% 6.7% 5.2% 8.7% 8.5% 5.3%

Lots Lot 1 (pg/ml) Lot 2 (pg/ml) Lot 3 (pg/ml) Lot 4 (pg/ml) Mean (pg/ml) Standard Deviation CV (%) Sample 1 107 122 102 116 111 7.75 6.9% Sample 2 712 667 661 672 678 20.01 2.9% Sample 3 1603 1507 1537 1543 1547 34.82 2.2% *number of samples for each test n=16.

15-25min

monoclonal antibody from mouse polyclonal antibody from goat

22367045

elisa-kits