Rat CXCL1/Gro Alpha ELISA Kit PicoKine® | Boster EK0724 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat CXCL1/Gro Alpha ELISA Kit PicoKine®

catalog :

EK0724

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0724

Product Name :

Rat CXCL1/Gro Alpha ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Rat CXCL1/Gro Alpha ELISA Kit PicoKine® (96 Tests). Quantitate Rat Cxcl1 in cell culture supernatants, serum and plasma (EDTA). Sensitivity: 1pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

CXCL1

Uniprot ID :

P14095

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: A25-K96

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<1 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Growth-regulated alpha protein

Synonyms :

Growth-regulated alpha protein;C-X-C motif chemokine 1;Cytokine-induced neutrophil chemoattractant 1;CINC-1;Platelet-derived growth factor-inducible protein KC;Cxcl1;Cinc1, Gro, Scyb1;

Protein Name :

Growth-regulated alpha protein

Molecular Weight :

10249 MW

Protein Function :

Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation.

Subcellular Localization :

Secreted.

Tissue Specificity :

At least expressed in the lung and trachea.

Background :

Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROalpha, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-alpha). In humans, this protein is encoded by the CXCL1 gene. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines. The mature form of CXCL1 is maximally 73 amino acids long. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2.CXCL1 decreased the severity of multiple sclerosis and may offer a neuro-protective function.

Research Category :

Cytokines, G Protein Signaling, Immunology, Innate Immunity, Signal Transduction, Signaling Pathway