Mouse CD86/B7-2 ELISA Kit PicoKine® | Boster EK0711 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse CD86/B7-2 ELISA Kit PicoKine®

catalog :

EK0711

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0711

Product Name :

Mouse CD86/B7-2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse CD86/B7-2 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Cd86 in cell culture supernatants and serum. Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

Cd86

Uniprot ID :

P42082

Immunogen :

Expression system for standard: NS0; Immunogen sequence: V26-G245

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants and serum

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

T-lymphocyte activation antigen CD86

Synonyms :

T-lymphocyte activation antigen CD86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;CD86;Cd86;

Protein Name :

T-lymphocyte activation antigen CD86

Molecular Weight :

34666 MW

Protein Function :

Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T- cells within 24 hours after activation.

Subcellular Localization :

Cell membrane ; Single-pass type I membrane protein .

Tissue Specificity :

Expressed on activated B-cells.

Background :

Cluster of Differentiation 86 (also known as CD86 and B7-2) is aprotein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. The CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. Using fluorescence in situ hybridization mapping, the CD86, like CD80, was mapped to human 3q21 and mouse chromosome 16, band B5. The antigen presentation coactivators B71 and B72, which are important in other immune-mediated thyroid diseases, are important for lymphocytic infiltration and the immune response against thyroid carcinoma.

Research Category :

Adaptive Immunity, Cell Type Markers, Hematopoietic Progenitors, Host Virus Interaction, Immunology, Interspecies Interaction, Lymphoid, Microbiology, Myeloid, Stem Cells, T Cells