Mouse CCL27/CTACK ELISA Kit PicoKine® | Boster EK0689 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse CCL27/CTACK ELISA Kit PicoKine®

catalog :

EK0689

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0689

Product Name :

Mouse CCL27/CTACK ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse CCL27/CTACK ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ccl27 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 12pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

Ccl27

Uniprot ID :

Q9Z1X0

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: L26-N120

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<12 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

C-C motif chemokine 27

Synonyms :

C-C motif chemokine 27;CC chemokine ILC;Cutaneous T-cell-attracting chemokine;CTACK;ESkine;IL-11 R-alpha-locus chemokine;ALP;mILC;Skinkine;Small-inducible cytokine A27;Ccl27;Ilc, Scya27;

Protein Name :

C-C motif chemokine 27

Molecular Weight :

13464 MW

Protein Function :

Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10.

Subcellular Localization :

Isoform 1: Secreted . Nucleus . May also be nuclear when following receptor (CCR10)-mediated internalization.

Tissue Specificity :

Isoform 1 is predominantly expressed in placenta and weakly in skin. Isoform 2 is predominantly expressed in testes and brain, weakly in kidney and liver and even lower in heart and muscle. Low expression of both isoforms in other tissues.

Background :

Chemokine (C-C motif) ligand 27 (CCL27) is a small cytokine belonging to the CC chemokine family, it is also known under the names IL-11 R-alpha-locus chemokine (ILC), Skinkine, ESkine and Cutaneous T-cell-attracting chemokine (CTACK). The human gene is mapped to 9p13.3. CCL27 is associated with homing of memory T lymphocytes to the skin, and plays a role in T cell-mediatedinflammation of the skin. And CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin. It elicits its chemotacticeffects by binding to the chemokine receptor CCR10.

Research Category :

Chemokines, Immunology, Innate Immunity