Human CA2 / Carbonic Anhydrase 2 ELISA Kit PicoKine® | Boster EK0681 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human CA2 / Carbonic Anhydrase 2 ELISA Kit PicoKine®

catalog :

EK0681

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0681

Product Name :

Human CA2 / Carbonic Anhydrase 2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human CA2 / Carbonic Anhydrase 2 ELISA Kit PicoKine® (96 Tests). Quantitate Human CA2 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate) and urine. Sensitivity: 50pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

CA2

Uniprot ID :

P00918

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: S2-K260

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

0.78 ng/ml - 50 ng/ml

Sensitivity :

<50 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA, citrate) and urine

Capture/Detection Antibodies :

A monoclonal antibody from mouse, a biotinylated detection polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

carbonic anhydrase 2

Synonyms :

Carbonic anhydrase 2; Carbonate dehydratase II; Carbonic anhydrase C; CAC; Carbonic anhydrase II; CA-II; CA2

Protein Function :

Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.

Subcellular Localization :

Cell membrane, Cytoplasm

Background :

CA2 is a cytosolic enzyme with the highest activity among all known CAs. The carbonic anhydrases (ACs) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. Mutations in the CA2 gene result in the CA II deficiency syndrome, an autosomal recessive disorder that produces osteopetrosis, renal tubular acidosis and cerebral calcification. This gene is mapped to 8q22.

Research Category :

Alzheimer'S Disease, Biochemicals, Cancer, Chemical Type, Diabetes, Heart Disease, Microbiology, Obesity